Website for the Revue de Médecine Vétérinaire

Detail of the article

[Back]

For articles published from January, 2000, you can reach the complete article as a pdf file by clicking on "pdf " in the column "Links" of the table.

Year : 2001
Tome : 152
Volume : 7
Pages : 515-521
Title : Iron metabolism and testing in the dog.
Authors : J.P. BRAUN, R. BACHELLERIE, J.F. GUELFI et P. LEBRETON.
Summary : In the dog as in other mammals, iron is a trace element mainly localized in hemoproteins such as hemoglobin and myoglobin. It is transported by transferrin in the plasma and stored by ferritin in organs, mainly in the liver. Only a very small fraction of iron is free ; it participates in exchanges and can generate potentially toxic radical oxygen species. Iron metabolism is based on low alimentary supply and elimination and high turnover of iron protein, which implies an intense recycling. Regulation is based on the translation of mRNAs for ferritin and transferrin receptors. Disturbances of iron metabolism occur mainly in anemias, portosystemic shunts and glucocorticoid treatments. Testing of iron metabolism is based on the hemogram and red cell parameters, iron concentration and TIBC (total iron binding capacity). Ferritinemia is the best test of iron stores in the body.
Keywords : dog - iron - plasma - ferritin - anemia -transferrin.
Correspondence : J.P. Braun
Adress : tél : +33 05 61 19 38 44, fax : +33 05 61 19 39 78, e-mail : jp.braun@envt.fr
Link : pdf

[Back]