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Year : 1993
Tome : 144
Volume : 10
Pages : 781-786
Title : Field application of closantel against ovine fascioliasis as part of an integrated control strategy
Authors : L. MAES, P. VEYS, H. GEERTS et O. CHIARISOLI
Summary : On a sheep farm with a high level of infection with Fasciola hepatica, closantel was used at 10 mg.kg orally in a 2-year integrated control programme. During the first year, all animals (approx. 400 ewes divided over 5 herds) were dosed 4 times at 6-week intervals, starting in late summer. Egg excretion immediately dropped to low levels and a good epidemiological and clinical control was maintained. Untreated tracer animals indicated that infections still occurred regularly. Related to the lowered level of infection and pasture contamination on the farm at the end of the first year, a less intensive dosing frequency (3 dosings at 8-10-week intervals) was subsequently adopted with good result. At the end of the trial, infection levels had dropped to less than 5 %. This trial clearly indicates that elimination of pasture contamination with fluke eggs forms an essential basis for a rapid and effective fluke control. Under conditions of high infection pressure, this can only be obtained using an intensive and strategic dosing regimen. Once infection has dropped to low levels, a basic control strategy of 3 dosings (September/October, December/Janary and May/June) will maintain optimal fluke control.
Keywords : closantel - Fasciola hepatica - strategic treatment - sheep.
Correspondence : L. MAES
Adress : Janssen pharmaceutica : Turnhoutseweg 30, Beerse, Belgique

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