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Year : 1994
Tome : 145
Volume : 1
Pages : 49-53
Title : Adhesion of Pasteurella multocida to HeLa cells and to macrophages of different animal species
Authors : J. ESSLINGER, R.S. SELEIM, G. HERRMANN et H. BLOBEL
Summary : All 14 P. multocida strains of serotype A adhered strongly to HeLa cells and to alveolar macrophages from rabbits, rats, mice, cattle and horses. Pasteurellae of serotypes B, D and E adhered weakly or not at all. The adhesions were markedly reduced by pretreatment of the pasteurellae with hyaluronidase or preincubation of the HeLa-cells with hyaluronic acid. This indicated a possible role of hyaluronic acid (contained in the capsules of serotype A) in adhesion and subsequent colonization of the bacteria.
Keywords : Pasteurella multocida - adhesion - rabbit -hyaluronic acid - macrophages.
Correspondence : J. ESSLINGER
Adress : Institute for Bacteriology and Immunology, Veterinary Faculty, Justus-Liebig-University, Frankfurter Strasse 107, D-35392 Giessen, Germany

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