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Year : 1994
Tome : 145
Volume : 6
Pages : 433-447
Title : Physiopathology of fever
Authors : H. SEBBAG
Summary : Fever, a syndrome consisting of hyperthermia and a number of other general signs, is part of the non-specific defences of many organisms. In response to different exogen pyrogens, fever is mediated by the endogen pyrogen, composed of cytokines of inflammation and of non-specific and specific immunity. Though it may be rather uncomfortable for the patient, fever has most often a positive effect against different aggressions. This defensive effect, as well as its role in diagnosis should incite to consider it well instead of using systematically antipyretics.
Keywords : fever - cytokine - non-specific immunity - specific immunity.
Correspondence : H. SEBBAG
Adress : ENV, CP 3013, F-44087 Nantes cedex 03

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