Website for the Revue de Médecine Vétérinaire

Detail of the article

[Back]

For articles published from January, 2000, you can reach the complete article as a pdf file by clicking on "pdf " in the column "Links" of the table.

Year : 2008
Tome : 159
Volume : 8-9
Pages : 437-443
Title : Haematological effects of dietary L-carnitine supplementation in broiler chickens
Authors : A. KARADENIZ, N. SIMSEK, S. CAKIR
Summary : The aim of the present experiment was to determine the effects of a dietary L-carnitine supplementation on haematological parameters in broiler chickens according to the energy level of the ration. Eighty one day old Ross 308 broiler chickens were equally divided into 4 groups (n = 20). Birds were fed with energy-depressed diets (groups I and II) or with normal energy diets (groups III and IV) supplemented with L carnitine (100 mg/kg of food) (groups II and IV) or not (groups I and III). Red blood cell (RBC) and white blood cell (WBC) counts, numeration of leukocyte types, packed cell volume (PCV) and haemoglobin concentrations were determined by haemocytometric methods on blood samples collected on last day of the 6 week trial period, and mean globular volumes (MGV) and mean corpuscular haemoglobin concentrations (MCHC) were calculated. After slaughter, heterophils or eosinophilic staining cells (ESC) were counted in lymphoid organs (thymus, spleen, caecal tonsil and bursa Fabricius). The L-carnitine treatment has induced significant increases of the RBC, WBC, heterophile and lymphocyte counts, of haemoglobin concentrations, PCV and MCHC compared to the respective controls whereas tissue ESC counts were significantly lowered in the spleen in the 2 supplemented groups and also in thymus medulla only when chickens received low energy diets (group II). Moreover, a correct dietary energy level has also improved erythropoiesis (increase of RBC counts) at a lesser extend, and diminished the inflammatory reaction in lymphoid organs (decrease of the tissue ESC counts). These results suggest that the dietary L-carnitine supplementation positively regulates erythropoiesis and inflammatory and immune cells and may restore them when the dietary energy supply is weakly depressed.
Keywords : L-carnitine, Broiler chicken, Low energy, Haematological parameters, Lymphoid organs
Correspondence : A. KARADENIZ
Adress : Department of Physiology, Faculty of Veterinary Medicine, University of Atatürk, 25 700 Erzurum, TURKEY. Email: karadenizali@atauni.edu.tr
Link : pdf

[Back]