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Year : 2007
Tome : 158
Volume : 12
Pages : 633-640
Title : Blood vitamin C, vitamin A, ?-carotene, ceruloplasmin, glutathione and malondialdehyde concentrations in cows with subclinical mastitis treated with intramammary antibiotics
Authors : BAYAZIT MUSAL, PINAR A. ULUTAS, SUHEYLA TURKYILMAZ
Summary : Antioxidant status (blood vitamin C, vitamin A, ?-carotene, glutathione and ceruloplasmin concentrations) and oxidative stress markers (malondialdehyde concentration) were analyzed in Holstein Frisian cows with subclinical mastitis (n = 24), the mammary infections being confirmed by CMT and bacteriological tests. According to the effectiveness of the intramammary antibiotherapy (200 mg Cephalexin and 100 000 IU Kanamycine), cows were divided into “cured” (n = 15, both CMT tests and bacteriological analysis of milk performed on days 14 and 21 were negative) and “not cured” (n = 9) (infection was still evidenced on days 14 and/or 21). Plasma MDA and blood antioxidant concentrations were determined on Days 14 and 21 post-treatment and compared with values obtained in healthy cows (n = 13). Blood vitamin C and glutathione concentrations in controls and cured cows were significantly higher than those of uncured cows. A significant rise in mean plasma vitamin Aconcentration was observed following intramammary therapy in cured cows, but a similar trend was also evident in the control group. No significant difference was observed in plasma ?-carotene, malondialdehyde and ceruloplasmin concentrations neither between groups or in repeated samplings of individual groups. It was concluded that subclinical mastitis significantly alters the antioxidant capacity in plasma of cows and that an efficient intramammary treatment partially restore the antioxidant status.
Keywords : Cow, oxidative stress, antioxidants, subclinical, mastitis, intramammary antibiotherapy
Correspondence : BAYAZIT MUSAL
Adress : Adnan Menderes University, Faculty of Veterinary Medicine, Department of Obstetrics and Reproductive Diseases, Aydin, TURKEY - E-mail: bmusal@adu.edu.tr
Link : pdf

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