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For articles published from January, 2000, you can reach the complete article as a pdf file by clicking on "pdf " in the column "Links" of the table.
| Year : | 2000 |
| Tome : | 151 |
| Volume : | 10 |
| Pages : | 931-936 |
| Title : | Escherichia coli lipopolysaccharide - induced experimental infection in piglets : clinical and laboratory findings |
| Authors : | I. BORISSOV and M. ANDONOVA |
| Summary : | In six female piglets aged 2-3 months weighing 28 ± 3 kg, an experimental infection has been provoked via the intravenous application of Escherichia coli 0111:B4 lipopolysaccharide (LPS) at a dose of 10 mg/kg b.w. The changes in clinical and laboratory parameters were followed out up to hour 72 following the treatment. It was determined that the first clinical signs, manifested with hyperthermia, anorexia and decreased activity appeared as early as 40 min after the LPS application. The infection was characterized with an initial leukopenia, followed by leukocytosis. The most prominent biochemical changes were expressed in hyperproteinemia, disproteinemia, increased serum sialic acid and urea levels and increased serum alanine aminotransferase (ALAT) and aspartate aminotransferase (ASAT) activities. |
| Keywords : | infection - lipopolysaccharide - clinical, haematological, biochemical findings - piglet. |
| Correspondence : | I. BORISSOV |
| Adress : | Department of Surgery Faculty of Veterinary Medicine, Thracian University, 6000 Stara Zagora, Bulgaria |
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