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Year :	1992
Tome :	143
Volume :	11
Pages :	825-830
Title :	Foal CD4 T lymphocytes decrease associated immunodeficiency.
Authors :	S. BENDALI-AHCENE, S. SAIAGH, J.L. CADORE, B. CLERC, M. FONTAINE et J.C. MONIER.
Summary :	IGRAM a eight month old foal suffering from strangles have been studied. A set of monoclonal antibodies (anti-CD5, CD4, CD8 and 12H9B11, 5B9C2) specific for T and B horse lymphocytes have been used to check the profile of lymphocytes subpopulations in this animal. We observed a striking decrease of peripheral CD4 cell population and of the CD4/CD8 ratio. This suggests, as in HIV infection in humans, that the immune system of horse may be the target of acquired immunodeficiences, perhaps of retroviral origin.
Keywords :	Monoclonal antibodies - Lymphocytes - Acquired immunodeficency - Foal.
Correspondence :	S. BENDALI-AHCENE
Adress :	Service de Pathologie Médicale des équidés et des carnivores, Ecole Nationale Vétérinaire de Lyon, 1, Av. Bourgelat, B,P. 83, F-69280 Marcy l'Etoile.

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