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Year : 1993
Tome : 144
Volume : 10
Pages : 739-744
Title : Blood ammonia in the dog. Factors of variation and diagnostic significance
Authors : L. DESMERIE, O. DOSSIN et J.P. BRAUN.
Summary : Ammonia is a toxic compound. Primarily produced in the gut, it is carried to the liver where it is converted to urea and then eliminated by the kidney. Hyperammonemia is usually secondary to severe hepatocellular insufficiency whatever its cause or to circulatory bypass of the liver. Some factors can also result in hyperammonemia without any liver disease. Blood ammonia and ammonia tolerance test can be performed as hepatic function assays. Ammonia concentration can now easily and quickly be measured by in practice chemistry analysers. However, specimen requirements must be respected and results must be linked to clinical features and other laboratory findings for interpretation.
Keywords : blood ammonia - ammonia tolerance test -liver - review -dog.
Correspondence : J.P. BRAUN.
Adress : Service de biochimie, ENVT, 23, chemin des capelles, F-31076 Toulouse cedex

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