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Year :	1995
Tome :	146
Volume :	7
Pages :	461-466
Title :	Urinary enzymes : markers of kidney tubule damage in dogs. A review.
Authors :	J.P. BRAUN, L. BRET, A.G. RICO, C. MÉDAILLE, J.P. PAGÉS et D. PÉCHEREAU.
Summary :	The measurement of urinary enzyme activities can contribute to the diagnosis of kidney damage, mainly of tubule damage. The elimination of enzymes varies along the day and their concentration depends on the diuresis. It is thus often recommended to calculate the ratio of their activity vs creatinine concentration. Whatever the cause of a kidney tubule damage, there is an early and intense increase in the excretion of gamma-glutamyl transferase, N-acetyl-beta-glucosaminidase and alkaline phosphatase. A more extensive use of these markers requires the validation of their measurement with biochemistry analyzers currently available in veterinary practices.
Keywords :	enzyme - urine - kidney damage - dog.
Correspondence :	J.P. BRAUN
Adress :	Département des Sciences biologiques et fonctionnelles et URA INRA Physiopathologie et toxicologie expérimentales, École Nationale Vétérinaire, 23, chemin des Capelles, F-31076 Toulouse Cedex

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